alexa Increasing spectrum of resistance in multiresistant Salmonella typhimurium.


Clinical Microbiology: Open Access

Author(s): EJ Threlfall, JA Frost, LR Ward, B Rowe

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SIR-Salmonella typhimurium definitive type 104 (DT 104) is now the second most prevalent salmonella in human beings in England and Wales, with isolations referred to the Laboratory of Enteric Pathogens increasing from fewer than 250 in 1990 to 2873 in 1994 and 3837 (provisional figure) in 1995. Of particular importance in this increase has been the epidemic spread of a multiresistant strain of R-type ACSSuT (A, ampicillin; C chloramphenicol; S, streptomycin, Su, sulphonamides; T, tetracyclines) (table). Molecular studies have demonstrated that in multiresistant DT 104 all these resistance genes are located on the chromosome,’ which is a rare phenomenon for S typhimurium.

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This article was published in Lancet and referenced in Clinical Microbiology: Open Access

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