alexa Induced pluripotent stem cells (iPSCs) and neurological disease modeling: progress and promises.
Molecular Biology

Molecular Biology

Journal of Cell Science & Therapy

Author(s): Marchetto MC, Brennand KJ, Boyer LF, Gage FH

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Abstract The systematic generation of neurons from patients with neurological disorders can provide important insights into disease pathology, progression and mechanism. This review will discuss recent progress in modeling neurodegenerative and neurodevelopmental diseases using induced pluripotent stem cells (iPSCs) and highlight some of the current challenges in the field. Combined with other technologies previously used to study brain disease, iPSC modeling has the promise to influence modern medicine on several fronts: early diagnosis, drug development and effective treatment.
This article was published in Hum Mol Genet and referenced in Journal of Cell Science & Therapy

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