alexa Infective stages of Leishmania in the sandfly vector and some observations on the mechanism of transmission.


Journal of Applied & Computational Mathematics

Author(s): Lainson R, Ryan L, Shaw JJ

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Abstract Infective stages of Leishmania (Leishmania) amazonensis, capable of producing amastigote infections in hamster skin, were shown to be present in the experimentally infected sandfly vector Lutzomyia flaviscutellata 15, 25, 40, 49, 70, 96 and 120 hours after the flies had received their infective blood-meal. Similarly, infective stages of Leishmania (L.) chagasi were demonstrated in the experimentally infected vector Lu. longipalpis examined 38, 50, 63, 87, 110, 135, 171 and 221 hours following the infective blood-meal, by the intraperitoneal inoculation of the flagellates into hamsters. The question of whether or not transmission by the bite of the sandfly is dependent on the presence of "metacyclic" promastigotes in the mouthparts of the vector is discussed.
This article was published in Mem Inst Oswaldo Cruz and referenced in Journal of Applied & Computational Mathematics

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