alexa Influence of surfactants on the physical stability of solid lipid nanoparticle (SLN) formulations.
Chemical Engineering

Chemical Engineering

Journal of Chemical Engineering & Process Technology

Author(s): Uner M, Wissing SA, Yener G, Mller RH

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Abstract The choice of surfactant or surfactant mixtures at suitable concentrations contributes to the stability of solid lipid nanoparticles (SLN). In this study, it was found that 1.5\% TegoCare 450 was the most effective stabilizer for the Witepsol E85 SLN dispersion compared to Tween 80, Tyloxapol and Pluronic F68 according to the data obtained from differential scanning calorimetry (DSC), zeta potential (ZP) measurements and particle size analysis.
This article was published in Pharmazie and referenced in Journal of Chemical Engineering & Process Technology

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