alexa Influenza seasonality: underlying causes and modeling theories
Infectious Diseases

Infectious Diseases

Journal of Infectious Diseases & Preventive Medicine

Author(s): Eric Lofgren, N H Fefferman, Y N Naumov, J Gorski, E N Naumova

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Influenza (or “flu”) leads to the hospitalization of more than 200,000 people yearly and results in 36,000 deaths from flu or flu-related complications in the United States (15), striking both the elderly and infant populations particularly hard (24). Two members of the Orthomyxoviridae family, the influenza A and B viruses, are the primary causes of this acute viral respiratory disease. Both viruses are characterized as enveloped viruses that contain eight negative-stranded RNA segments that encode 9 structural and 2 nonstructural proteins (influenza A virus) or 10 structural and 1 nonstructural protein (influenza B virus). Because of the higher levels of morbidity and mortality associated with influenza A virus, in part due to the large reservoir of the virus in aquatic birds, we will restrict ourselves to discussions of this virus.

This article was published in J. Virol and referenced in Journal of Infectious Diseases & Preventive Medicine

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