alexa Inhaled amorphous silica particulates: what do we know about their toxicological profiles?


Journal of Microbial & Biochemical Technology

Author(s): Warheit DB

Abstract Share this page

Abstract The International Agency for Research on Cancer (IARC) recently published a monograph on the evaluation of carcinogenic risks to humans of exposure to crystalline and amorphous silica particles. The IARC Working Group concluded that crystalline silica, in the form of quartz or cristobalite, from occupational sources posed a carcinogenic risk to humans (Category 1). IARC also determined that amorphous silica particles were not classifiable as to its carcinogenicity to humans (Category 3). With regard to amorphous silica, the evaluation was based primarily on the lack of toxicological and epidemiological data for these materials and this was noted in the IARC document. This manuscript is designed to provide a brief summary of the limited inhalation toxicity database related to amorphous silica particulates and to cite a few studies wherein the pulmonary toxicological effects of inhaled crystalline and amorphous silica particles were compared.
This article was published in J Environ Pathol Toxicol Oncol and referenced in Journal of Microbial & Biochemical Technology

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version