alexa Inhibition of growth of Chlamydia trachomatis by human gamma interferon.


Global Journal of Technology and Optimization

Author(s): Shemer Y, Sarov I

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Abstract Treatment of HEp-2 cell cultures with highly purified human gamma interferon before infection resulted in the reduction of Chlamydia trachomatis (L2/434/Bu) infectious particle yield. Electron microscope studies showed that interferon did not affect chlamydial conversion to reticulate bodies but influenced the extent of maturation to elementary bodies. High interferon concentrations (greater than 350 IU/ml) inhibited inclusion body formation and resulted in the appearance of aberrant reticulate bodies.
This article was published in Infect Immun and referenced in Global Journal of Technology and Optimization

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