alexa Initial combination of injectable and oral anti-tuberculosis agents for the treatment of severe disseminated tuberculosis.


Journal of Pulmonary & Respiratory Medicine

Author(s): Boff DF, Goldani LZ

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Abstract There is a need for intravenous therapy for severe forms of tuberculosis in those who are HIV-positive, diabetic, have cystic fibrosis, extensive gastrointestinal involvement, haemodynamic instability with difficulty to take and absorb oral medications, which results in a lack of appropriate therapeutic effect during treatment, such as not creating the optimal blood concentration of the substance. We report an HIV-infected patient presenting with severe disseminated tuberculosis with extensive intestinal involvement which was successfully treated with an initial combination regimen of injectable and oral anti-tuberculosis agents. We discuss and emphasize the importance of an initial regimen with injectable and oral agents for treating severe forms of tuberculosis. This article was published in Trop Doct and referenced in Journal of Pulmonary & Respiratory Medicine

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