Author(s): Berg RD, Ramakrishnan L
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Abstract Mycobacterium tuberculosis (MTB) continues to plague humanity because of significant gaps in our understanding of MTB infection, including the nature of a protective versus pathological host response, why antimicrobial cure is so difficult, and the ineffectiveness of vaccination. The development of a zebrafish model, utilizing infection with the natural fish pathogen Mycobacterium marinum (Mm), has yielded important insights into tuberculosis with immediate clinical applications. Copyright © 2012 Elsevier Ltd. All rights reserved.
This article was published in Trends Mol Med
and referenced in Journal of Clinical & Cellular Immunology