alexa Instability of large direct repeats in retrovirus vectors.
Genetics & Molecular Biology

Genetics & Molecular Biology

Journal of Molecular and Genetic Medicine

Author(s): Rhode BW, Emerman M, Temin HM

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Abstract Retrovirus vectors were constructed with large (0.85- to 1.3-kilobase-pair) direct repeats in their genomes. Deletions involving the direct repeats occurred at a high frequency. Deletions occurred both when the direct repeats were in tandem and when they were separated by additional sequences. These deletions occurred during virus replication.
This article was published in J Virol and referenced in Journal of Molecular and Genetic Medicine

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