Author(s): McCarty MF
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Abstract The recently reported association between insulin resistance and elevated plasma homocyst(e)ine may reflect the fact that hyperinsulinemia suppresses hepatocyte expression of cystathionine beta-synthase, as demonstrated in rats. Thus, other measures which enhance diurnal insulin secretion - such as a high-glycemic-index diet - can be expected to increase homocysteine levels.
This article was published in Med Hypotheses
and referenced in Journal of Pharmacogenomics & Pharmacoproteomics