Author(s): DeMali KA, Wennerberg K, Burridge K
Abstract Share this page
Abstract Integrin engagement stimulates the activity of numerous signaling molecules, including the Rho family of GTPases, tyrosine phosphatases, cAMP-dependent protein kinase and protein kinase C, and stimulates production of PtdIns(4,5)P2. Integrins promote actin assembly via the recruitment of molecules that directly activate the actin polymerization machinery or physically link it to sites of cell adhesion.
This article was published in Curr Opin Cell Biol
and referenced in Journal of Cytology & Histology