Author(s): Li L, Han DK, Lu J
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Abstract We report a case of severe thrombocytopenia following pegylated interferon-alpha 2a (Peg-IFN-alpha 2a) treatment of hepatitis C virus infection and summarize the clinical characteristics of 16 cases of IFN-alpha induced severe thrombocytopenia and its immune-mediated mechanism. Discontinuation of IFN-alpha and early administration of immunosuppressants are the effective therapy for IFN-alpha induced severe thrombocytopenia. 2010 Baishideng. All rights reserved.
This article was published in World J Gastroenterol
and referenced in Journal of Clinical & Cellular Immunology