alexa International cooperation and preparedness in responding to accidental or deliberate biological disasters: lessons and future directions.
General Science

General Science

Journal of Bioterrorism & Biodefense

Author(s): Lubroth J

Abstract Share this page

Abstract Preparations for international cooperation in response to disease disasters at the regional or continental levels are poorly coordinated and cooperation is limited, although intergovernmental and international organisations have been advocating for years that emergency responses to infectious disease outbreaks should be planned for and prepared at the national level. National governments are responsible for contingency planning to protect the public; however, this responsibility needs to be broadened to encompass regional and international approaches. Little public domain information is available on international coordinated responses to the deliberate introduction of biological pathogens. Terrorist events in the early 21st Century have increased awareness of the risks, but solid commitment and internationally resourced initiatives are still lacking. The current avian influenza disaster has largely been addressed by the three global agencies: Food and Agriculture Organization (FAO), World Organisation for Animal Health (OIE) and World Health Organization (WHO), using the underlying precepts that shape the Global Framework for the Progressive Control of Transboundary Animal Diseases (GF-TADs). The GF-TADs offers a substantial base to improve regional epidemiological and environmental information, diagnostic networking, trend analysis and intervention against the important epidemic animal diseases. International prevention, preparedness and response require multidisciplinary teams working in an environment of intergovernmental cooperation that encompasses numerous ministries and agencies. This paper focuses on known international aspects of collaboration on emergency preparedness and addresses the FAO/OIE initiative to strengthen veterinary and public health systems involved in controlling and preventing serious health threats.
This article was published in Rev Sci Tech and referenced in Journal of Bioterrorism & Biodefense

Relevant Expert PPTs

Relevant Speaker PPTs

  • Eugene Stephane Mananga
    On Fer and Floquet-Magnus expansions: Application in solid-state nuclear magnetic resonance and physics
    PDF Version
  • Yosef Yarden
    Classically, the 3’untranslated region (3’UTR) is that region in eukaryotic protein-coding genes from the translation termination codon to the polyA signal. It is transcribed as an integral part of the mRNA encoded by the gene. However, there exists another kind of RNA, which consists of the 3’UTR alone, without all other elements in mRNA such as 5’UTR and coding region. The importance of independent 3’UTR RNA (referred as I3’UTR) was prompted by results of artificially introducing such RNA species into malignant mammalian cells. Since 1991, we found that the middle part of the 3’UTR of the human nuclear factor for interleukin-6 (NF-IL6) or C/EBP gene exerted tumor suppression effect in vivo. Our subsequent studies showed that transfection of C/EBP 3’UTR led to down-regulation of several genes favorable for malignancy and to up-regulation of some genes favorable for phenotypic reversion. Also, it was shown that the sequences near the termini of the C/EBP 3’UTR were important for its tumor suppression activity. Then, the C/EBP 3’UTR was found to directly inhibit the phosphorylation activity of protein kinase CPKC in SMMC-7721, a hepatocarcinoma cell line. Recently, an AU-rich region in the C/EBP 3’UTR was found also to be responsible for its tumor suppression. Recently we have also found evidence that the independent C/EBP 3’UTR RNA is actually exists in human tissues, such as fetal liver and heart, pregnant uterus, senescent fibroblasts etc. Through 1990’s to 2000’s, world scientists found several 3’UTR RNAs that functioned as artificial independent RNAs in cancer cells and resulted in tumor suppression. Interestingly, majority of genes for these RNAs have promoter-like structures in their 3’UTR regions, although the existence of their transcribed products as independent 3’UTR RNAs is still to be confirmed. Our studies indicate that the independent 3’UTR RNA is a novel non-coding RNA species whose function should be the regulation not of the expression of their original mRNA, but of some essential life activities of the cell as a whole.
    PPT Version | PDF Version

Recommended Conferences

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords