Author(s): Tincello DG, Walker AC
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Abstract PURPOSE: To examine the site, severity, and duration, of symptoms in patients with interstitial cystitis. To examine the treatments offered. MATERIALS AND METHODS: Postal questionnaire administered to members of the Interstitial Cystitis Support Group, based in the United Kingdom. RESULTS: 736 of 1148 (64\%) questionnaires were returned. 696 (94.6\%) patients were women. 471 patients (64\%) described daily pain when symptoms were at their worst, and 273 (37\%) described daily pain at the time of survey. Most patients reported frequency, urgency and nocturia. A wide range of treatments had been offered, but drugs of proven efficacy were offered to less than a third of patients: cimetidine (36\%); antihistamines (5\%); pentosan polysulphate (12\%); DMSO (33\%); and anticonvulsants (2\%). 495 patients (67\%) reported "considerable impact" or more on their lifestyle and 346 (46\%) reported moderate depression or worse. 364 (49\%) reported at least considerable difficulties with sexual intercourse. CONCLUSIONS: This survey supports the work of others about the nature of symptoms and their impact upon quality of life. The data highlight the continuing difficulty in making a prompt diagnosis. We recommend that a European survey or registry of interstitial cystitis patients would help to establish a minimum standard of care. A suggested treatment algorithm is provided.
This article was published in Eur J Obstet Gynecol Reprod Biol
and referenced in Reproductive System & Sexual Disorders: Current Research