alexa Intracellular cargo delivery using tat peptide and derivatives.
Genetics & Molecular Biology

Genetics & Molecular Biology

Journal of Stem Cell Research & Therapy

Author(s): Zhao M, Weissleder R

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Abstract Efficient delivery of therapeutic and diagnostic agents across the plasma membrane is crucial in developing novel therapies. Membrane permeating peptides, in particular HIV-1 tat peptide and its derivatives, have enabled the intracellular delivery of cargos of various sizes and physicochemical properties. This review summarizes the current knowledge of tat-derived cell permeating peptides in the transduction of exogenous molecules/complexes. Copyright 2003 Wiley Periodicals, Inc. This article was published in Med Res Rev and referenced in Journal of Stem Cell Research & Therapy

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