alexa Intracranial steno-occlusive arterial disease and its associations in Egyptian ischemic stroke patients.


Journal of Vascular Medicine & Surgery

Author(s): Moustafa RR, Moneim AA, Salem HH, Shalash AS, Azmy HA

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Abstract BACKGROUND AND PURPOSE: Intracranial arterial steno-occlusive disease is prevalent among non-white populations. We explored whether a similar pattern exists in Egyptians and assessed its clinical-radiological associations. METHODS: Consecutive acute ischemic stroke patients were recruited for 6 months and had magnetic resonance imaging/magnetic resonance angiography of brain within 2 days of the event. Magnetic resonance angiography was analyzed for significant stenosis (>50\%), flow gaps, and complete occlusions in the major intracranial arteries. RESULTS: A total of 143 patients completed the study (62.4 ± 12.6 years, 58.7\% males). Magnetic resonance angiography showed symptomatic arterial stenosis in 27.3\%, asymptomatic stenosis in 16.1\%, and occlusions in 23.7\% patients. Carotid duplex showed stenosis >70\% in only 7.7\% patients. Patients with intracranial arterial steno-occlusive disease had higher National Institutes of Health Stroke Score at admission (10.9 ± 7 versus 8 ± 5.6; P=0.01). CONCLUSIONS: Symptomatic and asymptomatic intracranial arterial steno-occlusive disease was prevalent in this Egyptian acute stroke sample. This might have important implications on stroke management in this population. This article was published in Stroke and referenced in Journal of Vascular Medicine & Surgery

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