alexa Intramandibular inflammatory myofibroblastic tumor--a true neoplasm or reactive lesion?


Oral Health Case Reports

Author(s): Poh CF, Priddy RW, Dahlman DM, Poh CF, Priddy RW, Dahlman DM

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Abstract OBJECTIVE: Inflammatory myofibroblastic tumor (IMT) is an uncommon lesion reported to arise in various organs and by convention believed to be a nonneoplastic reactive inflammatory condition. Because of its radiographic and histologic similarities to malignancy, IMT can pose a considerable diagnostic dilemma. The purpose of this study is to report the first intramandibular IMT and to discuss the possible nature of this lesion. STUDY DESIGN: Detailed documentation of clinical, radiographic, and histologic features; literature review. RESULTS: This lesion showed distinct radiographic, histologic, and immunohistochemical features. The lesion recurred 14 months after initial removal with almost identical histology. CONCLUSION: This is the first documented case of an intramandibular IMT. Due to the rarity of these lesions, their clinical sequelae and prognosis are undetermined. As a result of specific immunohistochemical phenotyping and clinical behavior of this lesion, we favored a diagnosis of inflammatory myofibroblastic tumor. Wide excision with a long-term clinical follow-up is required. This article was published in Oral Surg Oral Med Oral Pathol Oral Radiol Endod and referenced in Oral Health Case Reports

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