Author(s): Eichler C, Hbbel A, Zarghooni V, Thomas A, Gluz O, , Eichler C, Hbbel A, Zarghooni V, Thomas A, Gluz O,
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Abstract AIM: The objective of this study was the investigation of a possible improvement of tumor resection rate, i.e. R0 vs. R1 resection when intraoperative ultrasound evaluation of tissue margins is used during breast-conserving surgery (BCS). PATIENTS AND METHODS: A total of 250 cases were evaluated retrospectively. The impact of ultrasound analysis onto clean margin rates was evaluated. A subgroup analysis assessed histology, stage, and neoadjuvant therapy with respect to R0 resection rate and ultrasound evaluation. RESULTS: Of 250 BCS cases 84, (33.6\%) underwent intraoperative ultrasound and 166 (66.4\%) did not. Clean primary surgical margins (R0) were demonstrated for 218 (87.2\%) patients after histological analysis. R0 resection was achieved in 81 (96.4\%) patients in the ultrasound group compared to 137 (82.5\%) in the control group. The difference between the two groups is significant. CONCLUSION: This study revealed a significant increase in R0 resection rates when intraoperative ultrasound was used to evaluate surgical margins.
This article was published in Anticancer Res
and referenced in Cancer Surgery