alexa Intraperitoneal Ropivacaine Irrigation in Patients Undergoing Bariatric Surgery: a Prospective Randomized Clinical Trial.
Medicine

Medicine

Internal Medicine: Open Access

Author(s): RuizTovar J, Gonzalez J, Garcia A, Cruz C, Rivas S,

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Abstract BACKGROUND: Despite most bariatric procedures are actually performed by laparoscopic approach, management of postoperative pain remains a major challenge. The aim of this study was to analyze the analgesic effect of intraperitoneal ropivacaine infusion in patients undergoing bariatric surgery. METHODS: A prospective randomized clinical trial of all the patients undergoing laparoscopic sleeve gastrectomy (LSG) or laparoscopic Roux-en-Y gastric bypass (LRYGB) between January and November 2015 was performed. Patients were randomized to experimental (EG: those patients undergoing intraperitoneal ropivacain irrigation) and control groups (CG: those undergoing intraperitoneal irrigation with normal saline). RESULTS: One hundred ten patients were included, 83 LRYGB (75.5 \%) and 27 LSG (24.5 \%). Mean pain, as measured by VAS score, was 21.7 ± 14.5 mm in CG and 13.3 ± 10.9 mm in EG (p = 0.002). Morphine needs during the first 24 h postoperatively were 21.8 \% in CG and 3.6 \% in EG (p = 0.01). Early taking of fluids by mouth was possible 6 h after surgery in 76.4 \% in EG vs 34.5 \% in CG (p = 0.001). Early mobilization ability (6 h after surgery) was feasible in 72.7 \% in EG and 32.7 \% in CG (p = 0.001). Median hospital stay was 3 days (range 2-10 days) in CG and 2 days (2-7 days) in EG (p = 0.009). CONCLUSIONS: The intraoperative peritoneal infusion with ropivacaine in patients undergoing bariatric surgery is associated with a reduction in postoperative pain, lower morphine needs, earlier mobilization and earlier oral intake of fluids after surgery, and a shorter hospital stay. ClinicalTrials.gov Identifier: NCT02641288. This article was published in Obes Surg and referenced in Internal Medicine: Open Access

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