alexa Intravenous glutamate enhances edema formation after a freezing lesion.


Journal of Neurology & Neurophysiology

Author(s): Kempski O, von Andrian U, Schrer L, Baethmann A, Kempski O, von Andrian U, Schrer L, Baethmann A

Abstract Share this page

Abstract The effect of intravenous infusion of glutamate on edema formation after a freezing lesion in rats is reported. Twenty-four hours of continuous intravenous glutamate application led to a significant increase of hemispheric swelling, and of the water and sodium content as compared with animals receiving infusions of physiological saline after trauma. The results suggest that glutamate entering the e.c. space together with the edema fluid causes additional cytotoxic edema as a consequence of an enhanced glutamate uptake by the glia. Therefore, the use of amino acid infusions containing glutamate for parenteral nutrition may present an additional risk for neurosurgical patients with a disturbed BBB.
This article was published in Adv Neurol and referenced in Journal of Neurology & Neurophysiology

Relevant Expert PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

1-702-714-7001Extn: 9037

Business & Management Journals


1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

1-702-714-7001 Extn: 9042

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version