alexa Introduction to the membrane protein reviews: the interplay of structure, dynamics, and environment in membrane protein function.


Journal of Physical Chemistry & Biophysics

Author(s): Sachs JN, Engelman DM, Sachs JN, Engelman DM, Sachs JN, Engelman DM, Sachs JN, Engelman DM

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Abstract In our review, we introduce an organizational scheme for membrane protein function. It is the relationship between structure, dynamics, and environment that endows the membrane and its constituents with remarkable sensitivity and robustness. Our understanding begins with landmark advances like those presented in the following chapters. Membrane proteins are notoriously difficult to study, and so the work presented here on the ADP/ATP carrier [Nury et al. ( 2 )], rhodopsin [Palczewski ( 24 )], and the cytochrome b6f complex [Cramer et al. ( 35 )] represents incredible progress in this now blossoming field. This article was published in Annu Rev Biochem and referenced in Journal of Physical Chemistry & Biophysics

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