alexa Investigation of various structures of DNA molecules (III) : Coil-globe transition of lambda-DNA induced by cationic surfactant.
Diabetes & Endocrinology

Diabetes & Endocrinology

Journal of Diabetes & Metabolism

Author(s): Feng X, Lin Z, Wang C, Bai C

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Abstract The structure transition of lambda-DNA induced by cationic surfactant cellar media was investigated by using CD, SEM and AFM. The experimental data of CD revealed that lambda-DNA can be induced from B-form to a collapsed structure with the addition of the cationic surfactant CTAB to the system. The condensed process of lambda-DNA from coil state to small globular state (diameter about 1.25 microm) and finally big globular state (diameter about 5.4 microm) was observed by using SEM and AFM. This article was published in Sci China C Life Sci and referenced in Journal of Diabetes & Metabolism

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