alexa Ionic substitutions in calcium phosphates synthesized at low temperature.


Bioceramics Development and Applications

Author(s): Boanini E, Gazzano M, Bigi A

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Abstract Ionic substitutions have been proposed as a tool to improve the biological performance of calcium phosphate based materials. This review provides an overview of the recent results achieved on ion-substituted calcium phosphates prepared at low temperature, i.e. by direct synthesis in aqueous medium or through hydrolysis of more soluble calcium phosphates. Particular attention is focused on several ions, including Si, Sr, Mg, Zn and Mn, which are attracting increasing interest for their possible biological role, and on the recent trends and developments in the applications of ion-substituted calcium phosphates in the biomedical field. Copyright 2009 Acta Materialia Inc. Published by Elsevier Ltd. All rights reserved. This article was published in Acta Biomater and referenced in Bioceramics Development and Applications

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