alexa Isolation and identification of compounds from Brazilian propolis which enhance macrophage spreading and mobility.


Journal of Microbial & Biochemical Technology

Author(s): Tatefuji T, Ohta T, Arai S, Izumi N, Ikeda M

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Brazilian propolis is known to induce the activation of murine effector cells. We isolated and identified six compounds from a water-soluble extract of Brazilian propolis, all of which have enhancing effects on the spreading and mobility of murine macrophages. These compounds were identified as caffeoylquinic acid-derivatives, namely, 5-caffeoylquinic acid (1), chlorogenic acid (2), 4-caffeoylquinic acid (3), 4,5-dicaffeoylquinic acid (4), 3,5-dicaffeoylquinic acid (5) and 3,4-dicaffeoylquinic acid (6).

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This article was published in Biol Pharm Bull. and referenced in Journal of Microbial & Biochemical Technology

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