Author(s): Hills SL, Griggs AC, Fischer M
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Abstract Japanese encephalitis (JE) is a severe disease and a risk for travelers who visit JE-endemic countries. We reviewed all published JE cases in travelers from non-endemic areas from 1973 through 2008, and assessed factors related to risk of infection. There were 55 cases that occurred in citizens of 17 countries. Age range of case-patients was 1-91 years (median = 34 years). Ten (18\%) persons died and 24 (44\%) had mild to severe sequelae. In a detailed risk assessment of 37 case-patients, 24 (65\%) had spent > or = 1 month in JE-endemic areas, and most had factors identified that may have increased infection risk. The estimate of overall JE risk was low, < 1 case/1 million travelers to JE-endemic countries. Nonetheless, for each traveler, a careful assessment of itinerary and activities, a decision on vaccination, and information on mosquito precautions are needed to reduce the risk of this disease.
This article was published in Am J Trop Med Hyg
and referenced in Journal of Infectious Diseases & Therapy