Author(s): Engel A, Fujiyoshi Y, Gonen T, Walz T
Abstract Share this page
Abstract Aquaporins (AQPs) are a family of ubiquitous membrane channels that conduct water and solutes across membranes. This review focuses on AQP0 and AQP4, which in addition to forming water channels also appear to play a role in cell adhesion. We discuss the recently determined structures of the membrane junctions mediated by these two AQPs, the mechanisms that regulate junction formation, and evidence that supports a role for AQP0 and AQP4 in cell adhesion.
This article was published in Curr Opin Struct Biol
and referenced in Journal of Clinical & Experimental Ophthalmology