Author(s): Urich SK, Chalcraft L, Schriefer ME, Yockey BM, Petersen JM
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Abstract Yersinia pestis is the causative agent of plague, a fulminant disease that is often fatal without antimicrobial treatment. Plasmid (IncA/C)-mediated multidrug resistance in Y. pestis was reported in 1995 in Madagascar and has generated considerable public health concern, most recently because of the identification of IncA/C multidrug-resistant plasmids in other zoonotic pathogens. Here, we demonstrate no resistance in 392 Y. pestis isolates from 17 countries to eight antimicrobials used for treatment or prophylaxis of plague.
This article was published in Antimicrob Agents Chemother
and referenced in Journal of Antivirals & Antiretrovirals