alexa Lactate measurements in critically ill patients with a hand-held analyser.


Journal of Antivirals & Antiretrovirals

Author(s): Brinkert W, Rommes JH, Bakker J

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Abstract OBJECTIVE: To compare a recently introduced hand-held lactate analyser to a reference point of care analyser (POCI) and the hospital laboratory in a critical care setting. SETTING: 10-bed surgical/medical intensive care unit in a teaching hospital. PATIENTS AND METHODS: In 39 critically ill patients, 50 convenience measurement cycles consisting of three paired measurements at 30-min intervals were carried out with a hand-held analyser, reference POCI and hospital laboratory using arterial blood samples. Duplicate measurements with the hand-held analyser were done in 129 blood samples. RESULTS: Lactate levels ranged from 1.1 to 21.0 mmol/l. Regression analysis of the hand-held analyser and laboratory showed a slope of 1.01, bias of -0.38 mmol/l, R(2) = 0.97 and mean error of 14.9 \%. Reference POCI versus laboratory: slope = 1.07, bias = -0.29 mmol/l, R(2) = 0.98 and mean error of 6.4 \%. Hand-held analyser versus reference POCI: slope = 0.90, bias = 0.09 mmol/l and R(2) = 0. 92. The hand-held analyser showed acceptable precision. CONCLUSION: The hand-held lactate analyser can reliably measure arterial blood lactate levels in critically ill patients.
This article was published in Intensive Care Med and referenced in Journal of Antivirals & Antiretrovirals

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