alexa Laparoscopic pancreaticoduodenectomy and distal pancreatectomy: a UK experience and a systematic review of the literature.
Molecular Biology

Molecular Biology

Journal of Cytology & Histology

Author(s): Ammori BJ, Ayiomamitis GD

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Abstract BACKGROUND: Advances in operative techniques and technology have facilitated laparoscopic distal pancreatectomy (LDP) and laparoscopic pancreaticoduodenectomy (LPD). METHODS: All distal pancreatectomies were attempted laparoscopically, while selected patients underwent LPD. The literature was systematically reviewed. RESULTS: Between 2002 and 2008, 21 patients underwent LDP (n=14) or LPD (n = 7). The mean operating time, blood loss, and hospital stay after LDP were 265 min, 262 ml, and 7.7 days, respectively, and after LPD they were 628 min, 350 ml, and 11.1 days, respectively. The conversion, morbidity, pancreatic fistula, readmission, reoperation, and mortality after LDP were 7.1, 35.7, 28.4, 28.4, 0, and 7.1\% respectively, and after LPD they were 0, 28.6, 14.3, 28.6, 0, and 0\% respectively. The literature review identified 987 LDP and 126 LPD. Most LDP were for benign disease (83.9\%) while most LPD were for malignancy (91.5\%). The mean operating time, morbidity, pancreatic fistula, mortality, and hospital stay after LDP were 221.5 min, 24.7\%, 16.4\%, 0.4\%, and 7.7 days, respectively, and after LPD they were 448.3 min, 28.6\%, 11.6\%, 2.1\%, and 16 days, respectively. CONCLUSION: LDP, particularly for benign disease and low-grade malignancy, is increasingly becoming the gold standard approach in experienced hands. In selected patients, LPD is feasible and safe. Long-term follow-up data are needed. This article was published in Surg Endosc and referenced in Journal of Cytology & Histology

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