alexa Laurencia filiformis: phytochemical profiling by conventional and HPLC-NMR approaches.
Psychiatry

Psychiatry

Journal of Addiction Research & Therapy

Author(s): Dias DA, White JM, Urban S

Abstract Share this page

Abstract Chemical investigation of the southern Australian marine alga Laurencia filiformis forma heteroclada resulted in the isolation of two new compounds, cycloisoallolaurinterol (16) and isoallolaurinterol (23), along with the previously reported sesquiterpenes filiformin (1), filiforminol (2), allolaurinterol (3) and bromolaurenisol (10). All structures were secured by detailed spectroscopic analysis since no previous 2D NMR studies had been described for compounds 1, 2 and 10. As a result of this study, the first single X-ray diffraction study for 1 was secured. The investigation of the chemical conversion of allolaurinterol (3) to filiformin (1) was monitored by on-flow HPLC-NMR, which also resulted in the identification of 23. We propose that both compounds 16 and 23 are formed as artefacts from allolaurinterol (3). HPLC-NMR was used to profile the crude extract of a marine organism, as well as for monitoring on-line compound chemical conversions. Both on-flow and stop-flow HPLC-NMR were successfully applied in the chemical profiling and compound chemical conversion studies of L. filiformis forma heteroclada. Compounds 2 and 3 displayed antimicrobial activities.
This article was published in Nat Prod Commun and referenced in Journal of Addiction Research & Therapy

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords