Author(s): Mimura M, Nakagome K, Hirashima N, Ishiwata H, Kamijima K,
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Abstract A 78-year-old housewife with major depression developed a right-sided infarction in the territory of the middle cerebral arteries, followed by acute post-stroke mania. Comparison between pre- and post-stroke SPECT scans demonstrated a unique pattern of left orbitofrontal hyperperfusion with extensive right frontal hypoperfusion. A functional imbalance between right and left orbitofrontal cortices may be important in mania.
This article was published in Psychiatry Res
and referenced in Journal of Addiction Research & Therapy