Author(s): Covarrubias EA, Sheikh MU, Solanki DL, Morjaria M, Fox LM, Covarrubias EA, Sheikh MU, Solanki DL, Morjaria M, Fox LM
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Abstract There is controversy in the medical literature regarding the significance of "sickle cell cardiomyopathy." In an attempt to clarify this, we studied 14 patients with sickle cell anemia (age range 16 to 36 years) using simultaneous echocardiography and phonocardiography. The values of systolic time intervals and echocardiographic indices of left ventricular performance were similar to those reported for normal subjects and those with comparable degrees of anemia. We confirm a previous report of normal left ventricular function at rest in patients with sickle cell anemia and concur with the suggestion that a concomitant heart disease be considered in these patients when cardiac failure supervenes.
This article was published in South Med J
and referenced in Journal of Blood Disorders & Transfusion