alexa Lesion of the subthalamic nucleus for the alleviation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism in the primate.
Clinical Research

Clinical Research

Journal of Clinical Research & Bioethics

Author(s): Aziz TZ, Peggs D, Sambrook MA, Crossman AR

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Abstract Central to the neural mechanism of MPTP-induced parkinsonism is overactivity of the subthalamic nucleus. Lesion of the subthalamic nucleus has therefore been performed in two primates with this condition and found to produce a remarkable amelioration of the disorder. This article was published in Mov Disord and referenced in Journal of Clinical Research & Bioethics

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