alexa Let me count the ways: mechanisms of gene regulation by miRNAs and siRNAs.
Molecular Biology

Molecular Biology

Journal of Cytology & Histology

Author(s): Wu L, Belasco JG

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Abstract The downregulation of gene expression by miRNAs and siRNAs is a complex process involving both translational repression and accelerated mRNA turnover, each of which appears to occur by multiple mechanisms. Moreover, under certain conditions, miRNAs are also capable of activating translation. A variety of cellular proteins have been implicated in these regulatory mechanisms, yet their exact roles remain largely unresolved. This article was published in Mol Cell and referenced in Journal of Cytology & Histology

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