Author(s): Feng J, Sethi A, ReyesMgica M, Antaya R
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Abstract We describe a 3-year-old girl with intractable, debilitating pruritus associated with a giant congenital melanocytic nevus, resulting in life-threatening anemia from extensive bleeding skin excoriations. Multiple conventional oral and topical antipruritic medications failed to provide relief, but the patient was successfully treated with the selective serotonin 5-hydroxytryptamine type 3 inhibitor ondansetron, suggesting a serotonin-related mechanism to her pruritus.
This article was published in J Am Acad Dermatol
and referenced in Dermatology and Dermatologic Diseases