alexa Light microscopic radioautographic study on DNA synthesis of nerve cells in the cerebella of aging mice.
Medicine

Medicine

Anatomy & Physiology: Current Research

Author(s): Cui H

Abstract Share this page

Abstract The morphological change and DNA synthesis of nerve cells in the cerebella of the aging mice were investigated by light microscopic radioautography using tritiated thymidine injection in vivo. During a period ranging from late fetal life to certain postnatal stages, 9 groups of mice were used. The labelled nuclei, which involved both the precursors of neurons and the glioblasts, were observed in the external granular layer of the cerebellum from embryonic day 19 to postnatal day 14. It disappeared completely at 1 month. A peak of labeling index was observed at postnatal day 3. The glioblasts of the external granular layer migrated inward, some of them forming the Bergmann glia cells located between Purkinje cells, this at postnatal day 8, some penetrating in the internal granular layer. Labelled nuclei in the internal granular layer were also observed and a maximum of the labeling was seen at postnatal day 3, similarly to the external granular layer. With the development and the expansion of the cerebellum, the endothelial cells of the cerebellar vessels were progressively labelled, reaching a maximum during the first postnatal week. The obtained results provided consequently some data on the age-related changes of DNA synthesis of mouse cerebellum from later embryonic stages to postnatal stages. Different investigations will be necessary to explain these irregular sequences of labeling.
This article was published in Cell Mol Biol (Noisy-le-grand) and referenced in Anatomy & Physiology: Current Research

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
 
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
 
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

Agri, Food, Aqua and Veterinary Science Journals

Dr. Krish

[email protected]

1-702-714-7001 Extn: 9040

Clinical and Biochemistry Journals

Datta A

[email protected]

1-702-714-7001Extn: 9037

Business & Management Journals

Ronald

[email protected]

1-702-714-7001Extn: 9042

Chemical Engineering and Chemistry Journals

Gabriel Shaw

[email protected]

1-702-714-7001 Extn: 9040

Earth & Environmental Sciences

Katie Wilson

[email protected]

1-702-714-7001Extn: 9042

Engineering Journals

James Franklin

[email protected]

1-702-714-7001Extn: 9042

General Science and Health care Journals

Andrea Jason

[email protected]

1-702-714-7001Extn: 9043

Genetics and Molecular Biology Journals

Anna Melissa

[email protected]

1-702-714-7001 Extn: 9006

Immunology & Microbiology Journals

David Gorantl

[email protected]

1-702-714-7001Extn: 9014

Informatics Journals

Stephanie Skinner

[email protected]

1-702-714-7001Extn: 9039

Material Sciences Journals

Rachle Green

[email protected]

1-702-714-7001Extn: 9039

Mathematics and Physics Journals

Jim Willison

[email protected]

1-702-714-7001 Extn: 9042

Medical Journals

Nimmi Anna

[email protected]

1-702-714-7001 Extn: 9038

Neuroscience & Psychology Journals

Nathan T

[email protected]

1-702-714-7001Extn: 9041

Pharmaceutical Sciences Journals

John Behannon

[email protected]

1-702-714-7001Extn: 9007

Social & Political Science Journals

Steve Harry

[email protected]

1-702-714-7001 Extn: 9042

 
© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version
adwords