alexa Lipid-nucleic acids interactions in vitro and in vivo


Journal of Chemical Biology & Therapeutics

Author(s): V V Kuvichkin

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The data on lipid-nucleic interactions and their role in vitro and in vivo are presented. The results of study of DNA-lipid complexes in absence and in presence of divalent metal cations (triple complexes) are discussed. The triple complexes represent the generation of cellular structures such as pore complexes of eucaryotes and "Bayer's junctions" of procaryotes. The participation of triple complexes in the formation of structure of bacterial and eucaryotic nucleoid and nuclear matrix is analysed. A model of formation of triple complexes and cellular structures and their role in DNA-lipid interactions are discussed.

This article was published in Bioelectrochemistry and referenced in Journal of Chemical Biology & Therapeutics

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