alexa Lipids on the move: simulations of membrane pores, domains, stalks and curves.
Bioinformatics & Systems Biology

Bioinformatics & Systems Biology

Current Synthetic and Systems Biology

Author(s): Marrink SJ, de Vries AH, Tieleman DP

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Abstract In this review we describe the state-of-the-art of computer simulation studies of lipid membranes. We focus on collective lipid-lipid and lipid-protein interactions that trigger deformations of the natural lamellar membrane state, showing that many important biological processes including self-aggregation of membrane components into domains, the formation of non-lamellar phases, and membrane poration and curving, are now amenable to detailed simulation studies. This article was published in Biochim Biophys Acta and referenced in Current Synthetic and Systems Biology

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