alexa Liposomal doxorubicin and nab-paclitaxel: nanoparticle cancer chemotherapy in current clinical use.
Materials Science

Materials Science

Journal of Nanomedicine & Nanotechnology

Author(s): Gaitanis A, Staal S

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Abstract Liposomal doxorubicin and nab-paclitaxel are nanoparticle formulations of traditional cancer chemotherapy drugs which have ample clinical experience both pre- and post-nanoparticle modification. The alterations in pharmacokinetics, pharmacodynamics, efficacy, and toxicity compared with their parent compounds are instructive for future development of nanoparticle-based therapies. In this article we review the current status of these agents, emphasizing the alterations in clinical behavior resulting from the nanoparticle formulation of the parent compound. This article was published in Methods Mol Biol and referenced in Journal of Nanomedicine & Nanotechnology

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