alexa Longitudinal changes in adaptive behavior in adults with Down syndrome: Interim findings from a longitudinal study.
Genetics & Molecular Biology

Genetics & Molecular Biology

Journal of Down Syndrome & Chromosome Abnormalities

Author(s): Prasher VP, Chung MC, Haque MS

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Age-related changes in adaptive behavior have been established in adults with Down syndrome. However, most studies have been cross-sectional, without controls for cohort and survival effects. We examined underlying factors for age-related decline in adaptive behavior in 128 adults with trisomy 21 over a 3-year period. Presence of dementia was the only determining factor, although the difference in trend over time as compared to subjects without dementia was not significant. No association between gender, sensory loss, severity of mental retardation, or place of residence was found. For subjects with no significant medical disorder (physical or psychological), no decline was seen. This longitudinal study confirms previously reported findings.

This article was published in Am J Ment Retard and referenced in Journal of Down Syndrome & Chromosome Abnormalities

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