alexa Long-lasting measles outbreak affecting several unrelated networks of unvaccinated persons.
Immunology

Immunology

Journal of Vaccines & Vaccination

Author(s): Dallaire F, De Serres G, Tremblay FW, Markowski F, Tipples G

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Abstract Despite a population immunity level estimated at approximately 95\%, an outbreak of measles responsible for 94 cases occurred in Quebec, Canada. Unlike previous outbreaks in which most unvaccinated children belonged to a single community, this outbreak had cases coming from several unrelated networks of unvaccinated persons dispersed in the population. No epidemiological link was found for about one-third of laboratory-confirmed cases. This outbreak demonstrated that minimal changes in the level of aggregation of unvaccinated individuals can lead to sustained transmission in highly vaccinated populations. Mathematical work is needed regarding the level of aggregation of unvaccinated individuals that would jeopardize elimination. This article was published in J Infect Dis and referenced in Journal of Vaccines & Vaccination

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