alexa Long-term anti-TNFalpha therapy for ankylosing spondylitis in two patients with chronic HBV infection.


Journal of Antivirals & Antiretrovirals

Author(s): Sakellariou GT, Chatzigiannis I

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Abstract Anti-TNFalpha therapy for rheumatic diseases appears to be safe in patients with chronic hepatitis C. However, the administration of anti-TNFalpha agents without initiation of prophylactic antiviral therapy (lamivudine 100 mg/day) in patients with chronic HBV infection results in exacerbation of liver disease. In this report, we describe our experience of long-term anti-TNFalpha therapy for ankylosing spondylitis in two inactive HBsAg carriers without preemptive antiviral treatment. This article was published in Clin Rheumatol and referenced in Journal of Antivirals & Antiretrovirals

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