alexa Low frequency of Toll-like receptors 2 and 4 gene polymorphisms in Mexican patients and their association with type 2 diabetes.
Diabetes & Endocrinology

Diabetes & Endocrinology

Journal of Diabetes & Metabolism

Author(s): MaldonadoBernal C, Trejode la O A, SnchezContreras ME, WacherRodarte N, Torres J,

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Abstract Type 2 diabetes (T2D) is characterized by a chronic low-grade inflammatory state. SNP in Toll-like receptor (TLR) genes has been associated with impaired inflammatory response. We genotyped the TLR4/D299G, TLR4/T399I and TLR2/R753Q polymorphisms. Low frequency was found with no association with T2D, nevertheless the TLR2 SNP was associated with lower levels in HDL-cholesterol values. © 2011 Blackwell Publishing Ltd. This article was published in Int J Immunogenet and referenced in Journal of Diabetes & Metabolism

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