alexa Lower brain-derived neurotrophic factor in serum of relapsing remitting MS: reversal by glatiramer acetate.


Journal of Clinical & Cellular Immunology

Author(s): Azoulay D, Vachapova V, Shihman B, Miler A, Karni A

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Abstract Neuronal growth factors may exert a neuroprotective effect in multiple sclerosis (MS). We found reduced levels of brain-derived neurotrophic factors (BDNF) in the serum and CSF of relapsing-remitting MS patients, which was reversed by therapy with glatiramer acetate. BDNF may play a protective role in MS, and immunomodulation therapy, such as with glatiramer acetate, may enhance the action this mechanism. This article was published in J Neuroimmunol and referenced in Journal of Clinical & Cellular Immunology

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