alexa LPS TLR4 signal transduction pathway.
Toxicology

Toxicology

Journal of Clinical Toxicology

Author(s): Lu YC, Yeh WC, Ohashi PS

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Abstract The stimulation of Toll-like receptor 4 (TLR4) by lipopolysaccharide (LPS) induces the release of critical proinflammatory cytokines that are necessary to activate potent immune responses. LPS/TLR4 signaling has been intensively studied in the past few years. Here we review molecules involved in TLR4-mediated signaling, including players that are involved in the negative regulation of this important pathway. This article was published in Cytokine and referenced in Journal of Clinical Toxicology

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