alexa Lung degassing: an evaluation of two methods.


Journal of Drug Metabolism & Toxicology

Author(s): Stengel PW, Frazer DG, Weber KC, Stengel PW, Frazer DG, Weber KC

Abstract Share this page

Abstract This study compares the effectiveness of the oxygen absorption and vacuum degassing methods for removing trapped gas from lungs. In addition, the effects of changing vacuum pressure, number of times to degas, and lung orientation during the vacuum degassing procedure were evaluated. To evaluate the two methods, a capacitance spirometer was designed and constructed to record lung volume as lungs were vacuum degassed. When lungs containing trapped gas were degassed in a vacuum chamber, they initially expanded, then slightly decreased in volume until the vacuum was released. Lung volume rapidly decreased as the pressure in the vacuum chamber returned to ambient pressure. The results showed that oxygen absorption atelectasis was more effective in removing gas from the lungs than vacuum degassing the lungs. When vacuum degassing was use, it was found to be most effective when the pressure in the chamber was reduced to the vaporization pressure of H2O and when the lungs were degassed twice. Degassing the lungs more than twice did not significantly remove more gas from the lungs. Lung orientation did not affect the removal of gas during vacuum degassing.
This article was published in J Appl Physiol Respir Environ Exerc Physiol and referenced in Journal of Drug Metabolism & Toxicology

Relevant Expert PPTs

Relevant Speaker PPTs

Recommended Conferences

Relevant Topics

Peer Reviewed Journals
Make the best use of Scientific Research and information from our 700 + peer reviewed, Open Access Journals
International Conferences 2017-18
Meet Inspiring Speakers and Experts at our 3000+ Global Annual Meetings

Contact Us

© 2008-2017 OMICS International - Open Access Publisher. Best viewed in Mozilla Firefox | Google Chrome | Above IE 7.0 version