alexa Lupane triterpenoids from Maytenus species.


Medicinal chemistry

Author(s): Nez MJ, Reyes CP, Jimnez IA, Moujir L, Bazzocchi IL

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Abstract Five new lupane triterpenes (1-5), in addition to 24 known ones, were isolated from Maytenus cuzcoina and M. chiapensis. Their structures were elucidated on the basis of spectroscopic analysis, including homonuclear and heteronuclear correlation NMR (COSY, ROESY, HSQC, and HMBC) experiments. The compounds were assayed for antimicrobial and cytotoxic activities, with 3-epi-betulinic acid and 28,30-dihydroxy-3-oxolup-20(29)-ene showing moderate cytotoxicity. This article was published in J Nat Prod and referenced in Medicinal chemistry

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