Author(s): Brennan TD, Miller AS, Chen SY
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Abstract PURPOSE: This study evaluated the demographics, treatment outcomes, histology, and basement lamina characteristics of a large series of lymphangiomas. MATERIAL AND METHODS: Forty-seven lymphangiomas of the oral cavity were evaluated microscopically and representative specimens were also evaluated immunohistochemically (IMH) and by electron microscopy (EM). RESULTS: Patient's ages ranged from 2 to 84 years. The dorsal surface of the tongue was the most common site. Discontinuities in the basement membrane were detected with IMH and EM. CONCLUSION: The discontinuous basement membrane may explain why sclerosing agents have not been effective as a form of treatment for lymphangioma.
This article was published in J Oral Maxillofac Surg
and referenced in Journal of Cancer Science & Therapy