alexa Malaria, monocytes, macrophages and myeloid dendritic cells: sticking of infected erythrocytes switches off host cells.
Infectious Diseases

Infectious Diseases

Malaria Control & Elimination

Author(s): Urban BC, Roberts DJ

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Abstract The adhesive phenotypes expressed by Plasmodium-falciparum-infected erythrocytes were previously thought simply to permit sequestration of parasites in the peripheral circulation. Recent work has illuminated how falciparum-infected erythrocytes may modulate the function of monocytes, macrophages and myeloid dendritic cells through the action of haemozoin from digested haemoglobin and through adhesion of infected cells to their surface.
This article was published in Curr Opin Immunol and referenced in Malaria Control & Elimination

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